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News on the Latest Fat-Fighting Ingredients!
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Submitted By RIVALUS Laboratories

Fat-Loss Supplement Research

With so many new research findings every year, it’s hard to keep up to date with the latest in supplement science. However, if your goal is to develop a lean, ripped physique then two new ingredients, raspberry ketone and campestenone, could be vital to help enhance your success! I’m going to explain exactly how these two exciting compounds can enhance fat loss and help you achieve your goals.

Raspberry Ketone

ImageRaspberry ketone (4-(4-hydroxyphenyl) butan-2-one) is a major aromatic compound derived from red raspberry. The structure of raspberry ketone is very similar to the structures of capsaicin and synephrine, both of which are known to have fat-burning properties due to altered lipid metabolism. In fact, raspberry ketone has been shown to increase norepinephrine induced lipolysis three times over norepinephrine alone. Essentially, raspberry ketone induces lipolysis by increasing the translocation of hormone-sensitive lipase (HSL) from the cytosol to lipid droplets in fat cells – this is the critical rate-limiting step at the beginning of lipolysis. Basically, HSL is the key enzyme involved in the mobilization of fatty acids from adipose tissue. However, on the other end of the fat-burning pathway (beta oxidation), a whole different group of enzymes are involved, and this is where the new ingredient campestenone has its effect.

Campestenone

Campestenone (campest-5-en-3-one) is a derivative of campesterol (24alpha-methyl-5-cholesten-3beta-ol), which is a compound that occurs naturally in various plants. New, cutting-edge research showed that campestenone dramatically increased the activities and the mRNA expressions of mitochondrial and peroxisomal enzymes involved in beta-oxidation (fat burning). This resulted in an increased rate of fat burning! Not to mention, campestenone also reduced the activities and the mRNA expressions of enzymes involved in fatty acid synthesis (fat creation) – therefore preventing fat build up! The research data even showed that campestenone was able to significantly increase energy expenditure. As a result, by combining raspberry ketone with campestenone you can affect the key fat-burning enzymes at both the beginning and end of the fat-burning pathway. Enhancing the activity of these rate-limiting enzymes could go a long way in helping you burn those extra pounds of unwanted body fat!

MPOWER by RIVALUS is the one product on the market that includes both raspberry ketone and campestenone in its formula along with many other unique fat burning ingredients. MPOWER is a one-of-a-kind supplement that’s been scientifically designed to increase energy and stimulate maximum fat loss – all at the same time!


References
Ikeda I, Konno R, Shimizu T, Ide T, Takahashi N, Kawada T, Nagao K, Inoue N, Yanagita T, Hamada T, Morinaga Y, Tomoyori H, Imaizumi K, Suzuki K. Campest-5-en-3-one, an oxidized derivative of campesterol, activates PPARalpha, promotes energy consumption and reduces visceral fat deposition in rats. Biochim Biophys Acta. 2006 May;1760(5):800-7. Epub 2006 Mar 23.

Morimoto C. Satoh Y. Hara M. Inoue S. Tsujita T. okuda H. Anti-obese action of raspberry ketone. Life Science 2005;77:194-204
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